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AI & Machine Learning -
Applications to Complex Genetic Diseases -
4D Nucleome -
Genomics, Gene Regulation & Epigenomics -
Multi-“omics” Integrative Bioinformatics -
Protein Structure, Proteomics & Alternative Splicing -
Systems Biology & Networks Analysis -
Translational Bioinformatics, Drug Discovery & Pharmacogenomics -
Grants -
Software & Bioinformatics Tools
As of October 23, 2024, the Gilbert S. Omenn Department of Computational Medicine & Bioinformatics has the following awards:
- 24 active awards where DCMB Faculty are PI’s: $12,280,062
- 101 active awards where DCMB are Co-I’s: $64,364,554
- 68 active awards where DCMB faculty are participating without effort $54,876,424
10 new grants in 2024
"Atlas-scale hierarchical identification of cell types and functions," Chan Zuckerberg Initiative (CZI), Joshua Welch
Continued Follow-up of Subjects and Initiation of a Second Case-control Cohort in The Environmental Determinants of Diabetes in The Young Study (TEDDY), National Institutes of Health, Department of Health and Human Services, Steven Parker
"Feasibility determination of retrospective clinical validation and extension of pharmacogenomics assays using patient-specific data and analytics," Phenomics Health, Inc, Brian Athey
"iReprogram's Partnership with the University of Michigan" - Supplement 1, iReprogram Inc., Indika Rajapakse
"PanKbase: a community hub for integrated pancreas knowledge," National Institutes of Health, Department of Health and Human Services, Jie Liu
"Single-Cell Multi-Omic Analysis of Cell Differentiation in HIV Infection," National Institutes of Health, Department of Health and Human Services, Joshua Welch
"Skeletal stem cell plasticity in craniofacial bone diseases," National Institutes of Health, Department of Human Health Services, Joshua Welch
"TwinCell Blueprint: Foundation for AI-assisted Cell Reprogramming," Department of Defense, Advanced Research Projects Agency, Indika Rajapakse
"Ultra-high resolution 3D genome maps for multiple human tissues," National Institutes of Health, Department of Human Health Services, Jie Liu
"Using the continuum of genetic causality to investigate trans regulatory mechanisms," National Institutes of Health, Department of Human Health Services, Steven Parker
In 2022, DCMB ranked #4 in NIH Grants in Biomedical Science departments.
Two NIH Training Grants
- “Biomedical Informatics and Data Science Training Program (BIDSTP)” - eight funded students per year for five years
Project Directors: Ivo Dinov and Ryan Mills - “Multi-Omics of Cancers Training Program” - seven funded students per year for five years
Project Directors: Maureen Sartor and Arvind Rao
NSF Grant
- “IUCRC Phase I University of Michigan Ann Arbor: Center for Data-Driven Drug Development and Treatment Assessment (DATA)” with U-M MIDAS
Department of Defense Grant
- “Data-guided Learning and Control of Higher Order Structures”