Gary J Fisher, PhD
Harry Helfman Professor of Molecular Dermatology
Professor of Dermatology
[email protected]

Available to mentor

Gary J Fisher, PhD
Professor
  • About
  • Center Memberships
  • Recent Publications
  • About

    Gary Fisher is the Harry Helfman Professor of Molecular Dermatology in the Department of Dermatology at the University of Michigan in Ann Arbor and Director of the Photoaging and Aging Research Program. He received his PhD from Cornell University in 1980 and received his postdoctoral training at Washington University in the Departments of Biological Chemistry and Laboratory Medicine.

    Dr. Fisher is mentor to junior faculty in translational research and to post-doctoral fellows, medical (at all levels) and diversity students in laboratory science. Also Dr. Fisher directs the basic science core curriculum course, which is taught to all residents in the Dermatology Department. Dr. Fisher has been a guest lecturer at NIH workshops and continuing education conferences for medical students and nurses alike.

    Dr. Fisher has received recognition as an inventor and by the dean for achievements in clinical and basic science research. He is associate editor for the Journal for Investigative Dermatology and Journal of Dermatological Science. In addition, he is a reviewer for several scholarly journals and is an invited speaker at major scientific meetings in the United States, Europe and Asia. Dr. Fisher is the author of over a hundred published papers.

    Dr. Fisher's research studies the molecular mechanisms of sun-induced premature skin aging and the molecular mechanisms of chronological skin aging focusing on four major areas: procollagen biosynthesis, collagen degradation, signal transduction, and inflammation. Dr. Fisher's laboratory works with the Clinical Research Unit (CRU), Cosmetic Laser Surgery Unit and Cutaneous Surgery and Oncology Unit. His additional current interests include mechanisms of protein phosphatases and stem cells in aging human skin.

    Center Memberships
    • Center Member
      Rogel Cancer Center
    Recent Publications See All Publications
    • Chapter
      Skin Ageing
      Pedersen EA, Fisher GJ, Voorhees JJ, Sachs DL. 2024 Apr; Rook's Textbook of Dermatology, DOI:10.1002/9781119709268.rook156
    • Journal Article
      Implications for cumulative and prolonged clinical improvement induced by cross-linked hyaluronic acid: An in vivo biochemical/microscopic study in humans.
      Wang F, Do TT, Smith N, Orringer JS, Kang S, Voorhees JJ, Fisher GJ. Exp Dermatol, 2024 Jan; 33 (1): e14998 DOI:10.1111/exd.14998
      PMID: 38284186
    • Journal Article
      Age-related changes in dermal collagen physical properties in human skin.
      He T, Fisher GJ, Kim AJ, Quan T. PLoS One, 2023 18 (12): e0292791 DOI:10.1371/journal.pone.0292791
      PMID: 38064445
    • Journal Article
      Matrix Metalloproteinase-1 Expression in Fibroblasts Accelerates Dermal Aging and Promotes Papilloma Development in Mouse Skin.
      Quan T, Xia W, He T, Calderone K, Bou-Gharios G, Voorhees JJ, Dlugosz AA, Fisher GJ. J Invest Dermatol, 2023 Sep; 143 (9): 1700 - 1707.e1. DOI:10.1016/j.jid.2023.02.028
      PMID: 36914001
    • Proceeding / Abstract / Poster
      1156 Single-cell RNA sequencing of photoaged skin reveals SLC46A2 as potential cGAMP transporter in keratinocytes
      Kim DJ, Billi A, Chien A, Fisher GJ, Voorhees JJ, Gudjonsson J, Kang S. Journal of Investigative Dermatology, 2023 May; 143 (5): s198 DOI:10.1016/j.jid.2023.03.1169
    • Proceeding / Abstract / Poster
      1171 Single-cell RNA sequencing confirms MMP2 as the primary matrix metalloproteinase implicated in the photoaging of keratinocytes
      Kim DJ, Chien A, Billi A, Fisher GJ, Voorhees JJ, Gudjonsson J, Kang S. Journal of Investigative Dermatology, 2023 May; 143 (5): s200 DOI:10.1016/j.jid.2023.03.1184
    • Journal Article
      1541 Co-transcription factors YAP and TAZ regulate dermal extracellular matrix homeostasis and scar formation in mouse skin
      Ermilov A, Qin Z, Kim A, Quan T, Voorhees JJ, Fisher GJ. Journal of Investigative Dermatology, 2023 May; 143 (5): s264 DOI:10.1016/j.jid.2023.03.1558
    • Journal Article
      363 Elevated expression of CCN1 in dermal fibroblasts causes accelerated dermal aging and promotes keratinocyte carcinogenesis
      Quan T, Kim A, Guo C, Xiang Y, Qin Z, Liu Y, Yan Y, Ermilov A, Voorhees JJ, Dlugosz A, Fisher GJ. Journal of Investigative Dermatology, 2023 May; 143 (5): s62 DOI:10.1016/j.jid.2023.03.368