Mrinal K Sarkar, PhD
Assistant Research Scientist
Dermatology
[email protected]

Available to mentor
Mrinal K Sarkar, PhD
Assistant Research Scientist
  • Research Overview
  • Recent Publications
    • Research Overview

    • Psoriasis
    • Cutaneous Lupus Erythematosus (CLE)
    • Keratinocytes
    • Type I Interferons
    • Systemic Lupus Erythematosus (SLE)
    • Interferon kappa

    Recent Publications See All Publications
    • Presentation
      "Generation of KO models in Keratinocytes and Fibroblasts for functional studies"
      Sarkar M, Patrick M. 2024 Jul 18;
    • Journal Article
      Targeting IL-1 controls refractory pityriasis rubra pilaris.
      Schmauch E, Severin Y, Xing X, Mangold A, Conrad C, Johannsen P, Kahlenberg JM, Mellett M, Navarini A, Nobbe S, Sarkar MK, Satyam A, Tsoi LC, French LE, Nilsson J, Linna-Kuosmanen S, Kaikkonen MU, Snijder B, Kellis M, Gudjonsson JE, Tsokos GC, Contassot E, Kolios AGA. Sci Adv, 2024 Jul 5; 10 (27): eado2365 DOI:10.1126/sciadv.ado2365
      PMID: 38959302
    • Journal Article
      Multi-ancestry Genome-Wide Association Meta-Analysis Identifies Novel Loci in Atopic Dermatitis.
      Oliva M, Sarkar MK, March ME, Saeidian AH, Mentch FD, Hsieh C-L, Tang F, Uppala R, Patrick MT, Li Q, Bogle R, Kahlenberg JM, Watson D, Glessner JT, Tsoi LC, Hakonarson H, Gudjonsson JE, Smith KM, Riley-Gillis B. medRxiv, 2024 Jun 19; DOI:10.1101/2024.06.17.24308897
      PMID: 38946956
    • Journal Article
      Suppression of TCF4 promotes a ZC3H12A-mediated self-sustaining inflammatory feedback cycle involving IL-17RA/IL-17RE epidermal signaling.
      Jiang Y, Gruszka D, Zeng C, Swindell WR, Gaskill C, Sorensen C, Brown W, Gangwar RS, Tsoi LC, Webster J, Sigurðardóttir SL, Sarkar MK, Uppala R, Kidder A, Xing X, Plazyo O, Xing E, Billi AC, Maverakis E, Kahlenberg JM, Gudjonsson JE, Ward NL. JCI Insight, 2024 Mar 12; 9 (8): DOI:10.1172/jci.insight.172764
      PMID: 38470486
    • Journal Article
      Phototherapy Restores Deficient Type I IFN Production and Enhances Antitumor Responses in Mycosis Fungoides.
      Yu Z, Vieyra-Garcia P, Benezeder T, Crouch JD, Kim IR, O'Malley JT, Devlin PM, Gehad A, Zhan Q, Gudjonsson JE, Sarkar MK, Kahlenberg JM, Gerard N, Teague JE, Kupper TS, LeBoeuf NR, Larocca C, Tawa M, Pomahac B, Talbot SG, Orgill DP, Wolf P, Clark RA. J Invest Dermatol, 2024 Mar; 144 (3): 621 - 632.e1. DOI:10.1016/j.jid.2023.06.212
      PMID: 37716650
    • Journal Article
      HERC6 regulates STING activity in a sex-biased manner through modulation of LATS2/VGLL3 Hippo signaling.
      Uppala R, Sarkar MK, Young KZ, Ma F, Vemulapalli P, Wasikowski R, Plazyo O, Swindell WR, Maverakis E, Gharaee-Kermani M, Billi AC, Tsoi LC, Kahlenberg JM, Gudjonsson JE. iScience, 2024 Feb 16; 27 (2): 108986 DOI:10.1016/j.isci.2024.108986
      PMID: 38327798
    • Journal Article
      Single-cell sequencing reveals Hippo signaling as a driver of fibrosis in hidradenitis suppurativa.
      van Straalen KR, Ma F, Tsou P-S, Plazyo O, Gharaee-Kermani M, Calbet M, Xing X, Sarkar MK, Uppala R, Harms PW, Wasikowski R, Nahlawi L, Nakamura M, Eshaq M, Wang C, Dobry C, Kozlow JH, Cherry-Bukowiec J, Brodie WD, Wolk K, Uluçkan Ö, Mattichak MN, Pellegrini M, Modlin RL, Maverakis E, Sabat R, Kahlenberg JM, Billi AC, Tsoi LC, Gudjonsson JE. J Clin Invest, 2024 Feb 1; 134 (3): DOI:10.1172/JCI169225
      PMID: 38051587
    • Journal Article
      A Critical Role for IFN-β Signaling for IFN-κ Induction in Keratinocytes.
      Xu B, Musai J, Tan YS, Hile GA, Swindell WR, Klein B, Qin JT, Sarkar MK, Gudjonsson JE, Kahlenberg JM. Front Lupus, 2024 2: DOI:10.3389/flupu.2024.1359714
      PMID: 38707772