Ormond A MacDougald
John A Faulkner Collegiate Professor of Physiology
Professor of Molecular and Integrative Physiology
Professor of Internal Medicine
[email protected]

Available to mentor

Ormond A MacDougald
Professor
  • About
  • Links
  • Qualifications
  • Center Memberships
  • Research Overview
  • Recent Publications
  • About

    After his postdoctoral fellowship in Dan Lane's lab at Johns Hopkins, Ormond MacDougald joined the U-M faculty as an Assistant Professor of Physiology. He currently is the John A Faulkner Collegiate Chair of Physiology and Professor of Molecular & Integrative Physiology, and Internal Medicine. Dr MacDougald’s professional interests include all aspects of adipose tissue biology. He is also dedicated to training the next generation of scientists.

    Dr. MacDougald has been recognized with numerous awards and accolades, including a Fulbright Scholar's Award. From U-M he is the recipient of the Rackham Distinguished Graduate Mentoring Award and the Basic Science Achievement Award. He also received the Henry Pickering Bowditch Award and the Bodil M. Schmidt-Nielsen Distinguished Mentor and Scientist Award from the APS, and is a Fellow of the American Association for the Advancement of Science.

    Outside work he mainly spends time with his wife and four children but he also likes to woodwork, garden, and make music.

    Links
    • MacDougald Lab Website
    Qualifications
    • Postdoctoral Fellow
      Johns Hopkins University School of Medicine, Biological Chemistry, 1996
    • Ph.D.
      Michigan State University, East Lansing, 1992
    • M.S.
      Michigan State University, East Lansing, 1988
    • B.Sc.
      University of Guelph, Guelph, 1986
    Center Memberships
    • Center Member
      Center for Cell Plasticity and Organ Design
    • Center Member
      Caswell Diabetes Institute
    Research Overview

    The MacDougald lab has broad interests in how adipocytes throughout the body develop, function, and interact with other cell types near and afar.

    Recent Publications See All Publications
    • Journal Article
      Scd1 and monounsaturated lipids are required for autophagy and survival of adipocytes.
      Mori H, Peterson SK, Simmermon RC, Overmyer KA, Nishii A, Paulsson E, Li Z, Jen A, Uranga RM, Maung JN, Yacawych WT, Lewis KT, Schill RL, Hetrick T, Seino R, Inoki K, Coon JJ, MacDougald OA. Mol Metab, 2024 Mar 14; 101916 DOI:10.1016/j.molmet.2024.101916
      PMID: 38492843
    • Preprint
      Dietary lipid is largely deposited in skin and rapidly affects insulating properties.
      Riley N, Kasza I, Barrett-Wilt G, Michaud J, Jain R, Trautman ME, Simcox JA, Yen C-LE, MacDougald OA, Lamming DW, Alexander CM. 2024 Feb 22; DOI:10.21203/rs.3.rs-3957002/v1
      PMID: 38464106
    • Journal Article
      Deciphering the Clinical Presentations in LMNA-related Lipodystrophy: Report of 115 Cases and a Systematic Review.
      Besci O, Foss de Freitas MC, Guidorizzi NR, Guler MC, Gilio D, Maung JN, Schill RL, Hoose KS, Obua BN, Gomes AD, Yıldırım Şimşir I, Demir K, Akinci B, MacDougald OA, Oral EA. J Clin Endocrinol Metab, 2024 Feb 20; 109 (3): e1204 - e1224. DOI:10.1210/clinem/dgad606
      PMID: 37843397
    • Journal Article
      TET3 plays a critical role in white adipose development and diet-induced remodeling.
      Jung BC, You D, Lee I, Li D, Schill RL, Ma K, Pi A, Song Z, Mu W-C, Wang T, MacDougald OA, Banks AS, Kang S. Cell Rep, 2023 Oct 31; 42 (10): 113196 DOI:10.1016/j.celrep.2023.113196
      PMID: 37777963
    • Preprint
      SCD1 and monounsaturated lipids are required for autophagy and survival of adipocytes.
      Mori H, Peterson SK, Simmermon R, Overmyer KA, Nishii A, Paulsson E, Li Z, Jen A, Uranga RM, Maung J, Yacawych WT, Lewis KT, Schill RL, Hetrick T, Seino R, Inoki K, Coon JJ, MacDougald OA. 2023 Oct 27; DOI:10.1101/2023.10.27.564376
      PMID: 37961537
    • Journal Article
      Adipose METTL14-Elicited N6 -Methyladenosine Promotes Obesity, Insulin Resistance, and NAFLD Through Suppressing β Adrenergic Signaling and Lipolysis.
      Kang Q, Zhu X, Ren D, Ky A, MacDougald OA, O'Rourke RW, Rui L. Adv Sci (Weinh), 2023 Oct; 10 (28): e2301645 DOI:10.1002/advs.202301645
      PMID: 37526326
    • Proceeding / Abstract / Poster
      FRI018 A Novel Truncating Variant Of EBF2 Disrupts Human Adipocyte Differentiation In Lipodystrophy Syndromes: An Example Of A Discovery From A Clinical Translational Pipeline
      de Freitas MCF, Wys N, Udler M, Pais L, da Rocha AM, MacDougald OA, Oral EA, Chun T-H. Journal of the Endocrine Society, 2023 Oct 5; 7 (Supplement_1): bvad114.029 DOI:10.1210/jendso/bvad114.029
    • Journal Article
      SAT650 Catecholamine-independent Neural Pathways Drive The Rapid Catabolism Of Metabolically Inert Fat
      Zhang X, Majumdar A, Kleiboeker B, Magee KL, Learman BS, Thomas SA, Lodhi IJ, MacDougald OA, Scheller EL. Journal of the Endocrine Society, 2023 Oct 5; 7 (Supplement_1): bvad114.098 DOI:10.1210/jendso/bvad114.098