David K Jones
Assistant Professor of Pharmacology
[email protected]

Available to mentor
David K Jones
Assistant Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Links
  • Recent Publications
    • Qualifications
    • K99 Fellowship
      University of Wisconsin-Madison, Neuroscience, 2019
    • Stem Cell and Regenerative Medicine
      University of Wisconsin-Madison, Neuroscience, 2018
    • Translational Cardiovascular Science
      University of Wisconsin-Madison, Neuroscience, 2016
    Center Memberships
    • Center Member
      Samuel and Jean Frankel Cardiovascular Center
    Research Overview

    Mechanisms and of cardia arrhythmia and dysfunction in the developing heart.
    Allosteric modulation of potassium channel gating to treat diseases of cardiac excitability.
    Neuronal comorbidities of cardiac electrical dysfunction.

    Links
    • Jones Lab
    Recent Publications See All Publications
    • Journal Article
      hERG1 channel subunit composition mediates proton inhibition of rapid delayed rectifier potassium current (IKr) in cardiomyocytes derived from hiPSCs.
      Ukachukwu CU, Jimenez-Vazquez EN, Jain A, Jones DK. J Biol Chem, 2023 Feb; 299 (2): 102778 DOI:10.1016/j.jbc.2022.102778
      PMID: 36496073
    • Journal Article
      KCNH2 encodes a nuclear-targeted polypeptide that mediates hERG1 channel gating and expression.
      Jain A, Stack O, Ghodrati S, Sanchez-Conde FG, Ukachukwu CU, Salwi S, Jimenez-Vazquez EN, Jones DK. Proc Natl Acad Sci U S A, 2023 Jan 17; 120 (3): e2214700120 DOI:10.1073/pnas.2214700120
      PMID: 36626562
    • Journal Article
      Enhancing iPSC-CM Maturation Using a Matrigel-Coated Micropatterned PDMS Substrate.
      Jimenez-Vazquez EN, Jain A, Jones DK. Curr Protoc, 2022 Nov; 2 (11): e601 DOI:10.1002/cpz1.601
      PMID: 36383047
    • Journal Article
      The ERG1 K+ Channel and Its Role in Neuronal Health and Disease.
      Sanchez-Conde FG, Jimenez-Vazquez EN, Auerbach DS, Jones DK. Front Mol Neurosci, 2022 15: 890368 DOI:10.3389/fnmol.2022.890368
      PMID: 35600076
    • Journal Article
      Hysteretic hERG channel gating current recorded at physiological temperature.
      Jones DK. Sci Rep, 2022 Apr 8; 12 (1): 5950 DOI:10.1038/s41598-022-10003-7
      PMID: 35396394
    • Journal Article
      Diversity of cells and signals in the cardiovascular system.
      Grandi E, Navedo MF, Saucerman JJ, Bers DM, Chiamvimonvat N, Dixon RE, Dobrev D, Gomez AM, Harraz OF, Hegyi B, Jones DK, Krogh-Madsen T, Murfee WL, Nystoriak MA, Posnack NG, Ripplinger CM, Veeraraghavan R, Weinberg S. J Physiol, 2023 Jul; 601 (13): 2547 - 2592. DOI:10.1113/JP284011
      PMID: 36744541
    • Preprint
      hERG1 channel subunit composition mediates proton inhibition of IKr in hiPSC-CMs
      Ukachukwu C, Jimenez-Vazquez E, Jain A, Jones D. 2022 Aug 27; bioRxiv, DOI:10.1101/2022.08.26.505466
    • Preprint
      <i>KCNH2</i>encodes a nuclear-targeted polypeptide that mediates hERG1 channel gating and expression
      Jain A, Stack O, Ghodrati S, Sanchez-Conde F, Ukachukwu C, Salwi S, Jimenez-Vazquez E, Jones D. 2022 bioRxiv, DOI:10.1101/2022.08.24.504830
    Featured News & Stories
    Department News
    David Jones receives Elizabeth Caroline Crosby Grant
    David Jones, PhD, Assistant Professor of Pharmacology and Assistant Professor of Internal Medicine, has been awarded the Elizabeth Caroline Crosby Grant.