Rachel Leigh Byerley Reinert
Assistant Professor of Internal Medicine
Internal Medicine, Division of Metabolism, Endocrinology & Diabetes
1000 Wall Street, 5132 Brehm Tower
Ann Arbor, MI 48105
[email protected]

Available to mentor
Rachel Leigh Byerley Reinert
Assistant Professor
  • Qualifications
  • Center Memberships
  • Research Overview
  • Links
  • Recent Publications
    • Qualifications
    • Fellowship
      University of Michigan, Internal Medicine; Division of Metabolism, Endocrinology & Diabetes, 2019
    • Residency
      University of Michigan, Internal Medicine, 2019
    • MD
      Vanderbilt University School of Medicine, 2201 West End, 2014
    • PhD
      Vanderbilt University, Medical Scientist Training Program, 2201 West End, 2012
    • BS
      University of Southern Indiana, Evansville, 2005
    Center Memberships
    • Center Member
      Caswell Diabetes Institute
    Research Overview

    Pancreatic islet cells are responsible for synthesizing, packaging, and secreting glucose-regulating hormones, including insulin and glucagon. Disruption of these processes contributes to hyperglycemia in diabetes mellitus. My laboratory group studies how cellular protein quality control mechanisms regulate hormone processing and define islet cell function.

    Links
    Recent Publications See All Publications
    • Journal Article
      Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding.
      Reinert RB, Cai Q, Hong J-Y, Plank JL, Aamodt K, Prasad N, Aramandla R, Dai C, Levy SE, Pozzi A, Labosky PA, Wright CVE, Brissova M, Powers AC. Development, 2014 Apr; 141 (7): 1480 - 1491. DOI:10.1242/dev.098657
      PMID: 24574008
    • Journal Article
      Tamoxifen-Induced Cre-loxP Recombination Is Prolonged in Pancreatic Islets of Adult Mice.
      Reinert RB, Kantz J, Misfeldt AA, Poffenberger G, Gannon M, Brissova M, Powers AC. PLoS One, 2012 7 (3): e33529 DOI:10.1371/journal.pone.0033529
      PMID: 22470452
    • Journal Article
      Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.
      Wicksteed B, Brissova M, Yan W, Opland DM, Plank JL, Reinert RB, Dickson LM, Tamarina NA, Philipson LH, Shostak A, Bernal-Mizrachi E, Elghazi L, Roe MW, Labosky PA, Myers MG, Gannon M, Powers AC, Dempsey PJ. Diabetes, 2010 Dec; 59 (12): 3090 - 3098. DOI:10.2337/db10-0624
      PMID: 20802254
    • Journal Article
      289-OR: Autophagy Promotes Islet α-Cell Function by Maintaining ER Proteostasis and Glucagon Production
      ZHU W, PAN L, CHIARA RUSSO A, RAY R, PEDERSON B, SHRESTHA N, QI L, REINERT RB. Diabetes, 2024 Jun 14; 73 (Supplement_1): DOI:10.2337/db24-289-or
    • Journal Article
      A Novel Receivership Model for Transition of Young Adults With Diabetes: Experience From a Single-center Academic Transition Program.
      Iyengar JJ, Ang L, Rodeman KB, Rao A, Lin YK, Broome DT, Fanous N, Reinert RB, Konigsberg A, Weatherup E, Hagar C, Rogosch D, Florek J, Carey B, Wyckoff J, Lee J, Thomas IH, Soleimanpour SA. Endocr Pract, 2024 Feb; 30 (2): 113 - 121. DOI:10.1016/j.eprac.2023.11.008
      PMID: 38029926
    • Journal Article
      Muscle-specific ER-associated degradation maintains postnatal muscle hypertrophy and systemic energy metabolism.
      Abdon B, Liang Y, da Luz Scheffer D, Torres M, Shrestha N, Reinert RB, Lu Y, Pederson B, Bugarin-Lapuz A, Kersten S, Qi L. JCI Insight, 2023 Aug 3; 8 (17): DOI:10.1172/jci.insight.170387
      PMID: 37535424
    • Proceeding / Abstract / Poster
      1768-P: Sel1L-Hrd1 Endoplasmic Reticulum-Associated Degradation Regulates PC2 Function and Proglucagon Processing in Islet α-Cells
      REINERT RB, ZHU W, PAN L, CHIARA RUSSO A, RAY R, SHRESTHA N, LINDBERG I, Qi LING. Diabetes, 2023 Jun 25; 72 (Supplement_1): DOI:10.2337/db23-1768-p
    • Journal Article
      Human pancreatic capillaries and nerve fibers persist in type 1 diabetes despite beta cell loss.
      Richardson TM, Saunders DC, Haliyur R, Shrestha S, Cartailler J-P, Reinert RB, Petronglo J, Bottino R, Aramandla R, Bradley AM, Jenkins R, Phillips S, Kang H, Human Pancreas Analysis Program , Caicedo A, Powers AC, Brissova M. Am J Physiol Endocrinol Metab, 2023 Mar 1; 324 (3): E251 - E267. DOI:10.1152/ajpendo.00246.2022
      PMID: 36696598