At the University of Michigan Medical School Department of Microbiology & Immunology, we study the basic questions relating to the role of T and B lymphocytes in adaptive immunity. Many of us seek to understand adaptive immunity at a molecular level in whole animals. These studies provide important insights into the function of the adaptive immune system in health and disease.
Learn more below about our areas of investigation and view a list of faculty members conducting research on adaptive immunity.
We investigate:
- Intracellular signaling mechanisms regulating T cell development and activation
- Immunoglobulin class switch recombination in B cells using techniques such as bacterial artificial chromosome transgenesis
- The behavior of T cells as regulators of adaptive immune responses and as effector cells is examined in bacterial infection and organ transplantation models using combined cellular and molecular approaches.
- The mechanisms involved in processing of antigen for recognition by T cells, including intracellular assembly of major histocompatibility complex class I proteins, and their altered trafficking in virus-infected cells
We are using the latest techniques and technology, including genome engineering methods.
Clinical Associate Professor of Pathology
Clinical Associate Professor of Microbiology and Immunology
Medical Director, Clinical Microbiology Laboratory
Program Director, Clinical Research
Clinical Pathology Division
Clinical Associate Professor of Microbiology and Immunology
Medical Director, Clinical Microbiology Laboratory
Program Director, Clinical Research
Clinical Pathology Division
Professor
Professor of Internal Medicine
Professor of Microbiology and Immunology
Associate Dean for Physician Scientist Education and Training
Professor of Microbiology and Immunology
Associate Dean for Physician Scientist Education and Training
Center Member
Professor of Microbiology and Immunology
Program Director
Microbiology and Immunology Mentoring Program
Professor of Microbiology and Immunology
Microbiology and Immunology Mentoring Program
Professor of Microbiology and Immunology
Program Director, Microbiology and Immunology DEI Initiatives
Associate Professor of Microbiology and Immunology
Associate Professor of Microbiology and Immunology
Nancy Walls Professor of Microbiology and Immunology
Chair, Department of Microbiology and Immunology
Professor of Microbiology and Immunology and Professor of Internal Medicine
Chair, Department of Microbiology and Immunology
Professor of Microbiology and Immunology and Professor of Internal Medicine
Professor of Internal Medicine
Professor of Microbiology and Immunology
Professor of Microbiology and Immunology
Professor Emeritus/A in Service of Surgery
Professor Emeritus of Microbiology and Immunology
Professor Emeritus of Microbiology and Immunology
Nancy Walls Research Professor of Microbiology and Immunology
Professor of Microbiology and Immunology
Professor of Microbiology and Immunology
Assistant Professor of Microbiology and Immunology
